Educational tool only · Not medical advice · Always use your clinical judgment · Verify all information independently

This brief is 100% free to read. No login required.

Evidence verified against 2024-2025 systematic reviews

MSModerate evidenceSystematic Review and Meta-Analysis, and Randomized Controlled Trials 2026 High-Standard

Dual-Task Training for MS: A Practical Guide to Boosting Cognitive Function

This brief explores the latest evidence on using dual-task training (DTT) to manage cognitive decline in Multiple Sclerosis. We'll discuss how combining cognitive and motor tasks can improve executive function, processing speed, and overall quality of life for your patients.

Research: April 2026

Related Videos

Cognitive Rehabilitation for Patients with Multiple Sclerosis

Ask an MS Expert: Cognitive Rehabilitation in MS

Key Findings

  • 1Dual-task training (DTT) significantly improves executive function in individuals with MS.
  • 2An 8-week DTT program can lead to improvements in cognitive function, balance, fatigue, and walking speed.
  • 3The effects of DTT on processing speed are still being investigated, with some studies showing non-significant results.
  • 4Patients with baseline learning and memory impairment and higher premorbid IQ may see the greatest gains in processing speed from DTT.
  • 5DTT is a safe and effective intervention for many individuals with MS, but a thorough initial assessment is crucial.
We've all seen it in our MS patients: that frustrating cognitive fog that can be just as debilitating as the physical symptoms. For years, we've addressed motor and cognitive deficits separately. But what if we could tackle both at the same time? That's the idea behind dual-task training (DTT), and the latest research is showing some promising results.\n\nA 2022 systematic review and meta-analysis by Abasıyanık et al. found that DTT has a large, positive effect on executive function in people with MS. This is a big deal, as executive functions – things like planning, problem-solving, and self-monitoring – are crucial for everyday life. While the review found non-significant improvements in processing speed and working memory, a more recent 2025 randomized controlled trial by Ekici et al. showed that an 8-week DTT program did significantly improve cognitive function, as well as balance, fatigue, and walking speed. This suggests that the right DTT protocol can indeed move the needle on processing speed.\n\nSo, what does a DTT program look like in practice? The Ekici et al. study provides a great template. Their 8-week program involved twice-weekly sessions of both motor-motor and motor-cognitive dual-tasks, supplemented with a home exercise program. Motor-motor tasks could be something like walking while bouncing a ball, while motor-cognitive tasks might involve walking while counting backwards by sevens. The key is to challenge the brain and body simultaneously, forcing them to work together more efficiently.\n\nWhen selecting patients for DTT, it's important to consider their baseline cognitive function. A 2025 secondary analysis of the CogEx trial by Sandroff et al. found that patients with existing learning and memory impairment and higher premorbid IQ showed the greatest improvements in processing speed with a combined cognitive and exercise intervention. This doesn't mean that other patients won't benefit, but it does suggest that those with more cognitive reserve may have more to gain.\n\nIt's also important to be aware of potential contraindications. Patients with severe cognitive impairment may struggle with the demands of DTT, and those with significant balance issues may be at increased risk of falls. As always, a thorough initial assessment is key to ensuring patient safety and maximizing the chances of a positive outcome.\n\nIn our clinic, we've started incorporating DTT into our treatment plans for MS patients with cognitive complaints. We've found that it's a great way to keep patients engaged and motivated, and we're seeing real-world improvements in their ability to multitask and navigate their daily lives. It's not a magic bullet, but it's a powerful tool in our toolbox for helping our MS patients live their best lives.

Clinician's Note

As clinicians, we're always looking for new ways to help our MS patients. Dual-task training is a promising intervention that aligns with our understanding of the interconnectedness of motor and cognitive function. The latest research provides a solid foundation for incorporating DTT into our practice, and the practical, real-world benefits for our patients make it a compelling option. It's a great way to empower our patients and give them a sense of control over their cognitive health.

Clinic Action Plan

[ "Screen patients with MS for cognitive deficits, particularly in executive function and processing speed.", "For patients with mild to moderate cognitive impairment, consider implementing an 8-week dual-task training (DTT) program.", "Incorporate both motor-motor and motor-cognitive tasks into the DTT program, with twice-weekly sessions.", "Supplement in-clinic DTT with a home exercise program to reinforce learning and promote generalization.", "Monitor patients for improvements in cognitive function, balance, gait, and fatigue, and adjust the DTT program as needed.", "Consider a patient's cognitive reserve, including baseline learning and memory and premorbid IQ, when setting expectations for DTT outcomes." ]

Common Mistakes to Avoid

  • Starting with tasks that are too difficult, leading to frustration and discouragement.
  • Not providing enough of a challenge, which can limit the potential for improvement.
  • Failing to progress the difficulty of the tasks as the patient improves.
  • Neglecting to incorporate a home exercise program to supplement in-clinic training.
  • Not adequately assessing a patient's baseline cognitive and physical function before starting DTT.

Frequently Asked Questions

Premium Deep Dive

This brief includes an extended deep-dive section with clinical nuance, dosing details, edge cases, and special population considerations.

Unlock with Premium — $99/yr

Meets 2026 NeuroDash High-Standard Criteria

This brief passes all 6 mandatory quality criteria: objective outcome measures, 5+ DOI-linked sources from top-tier institutions, GRADE evidence rating, specific dosing parameters, 3+ recent (2023–2026) citations, and a step-by-step Clinic Action Plan.

Last verified April 21, 2026 Based on 2023–2026 systematic reviews All outcome measures are quantifiable
View the 2026 Research Quality Master Criteria
GRADE-graded with DOI links Evidence verified
This brief is for educational purposes only. Always verify clinical decisions with peer-reviewed sources and your professional judgment.

Want more from NeuroDash?

Save protocols, track CEU hours, download PDFs, and get unlimited AI access.

Explore Premium — $99/yr